César de la Fuente Lab Uses Codex and ChatGPT to Mine Genomes for New Antimicrobials

Addressing the growing crisis of antibiotic-resistant pathogens, César de la Fuente’s laboratory at the University of Pennsylvania is employing Codex and ChatGPT within their computational biology pipeline. By systematically screening genomic sequences from both living organisms and extinct species, the team accelerates the identification of novel antimicrobial peptide candidates, demonstrating how code- and language-centric models can assist molecular discovery across evolutionary datasets.